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2B78
IE00BYZK4776
2B78 ETF · iShares Healthcare Innovation UCITS ETF
The 2B78 Exchange Traded Fund (ETF) is provided by iShares. It is built to track an index: STOXX Global Breakthrough Healthcare Index. The 2B78 ETF provides physical exposure, so by buying it you actually own parts of all the 173 underlying holdings. The dividend policy is capitalization.
Last update 3/13/2026, 7:00 AM UTC
LIVE
CLOSED
This fund is part ofWorld Blended Cap1M perf.-3.65%
Last price
€7.45
1M perf.
-5.22%
1M flows
-€7.8M
AuM
€866M
E/R
0.4%
Rating
ESG Consensus®
2B78
€7.45
Performance & flows
Segment for quartile rank
December 15, 2025 → March 13, 2026
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2B78
$8.56
-4.98%
World Blended Cap
+0.71%
Historic performance and flows
| 1M | 3M | 1Y | 3Y | 5Y | MTD | QTD | YTD | ||
|---|---|---|---|---|---|---|---|---|---|
| Perf. | -5.22%  | -4.98% | +14.22% | +20.34% | -14.40% | -7.53% | -4.90% | -4.90% | |
| Flows |
Key fund info
Segment for quartile rank
Main characteristics
More details
NAV
3/13/2026
$8.56
1D NAV change
-0.58%
Dividend policy
Replication method
Direct (Physical)
Replication model
Optimized sampling
No. of holdings
173
Inception date
9/8/2016
Jurisdiction
Ireland
Distribution
Portugal
Ireland
Chile
Spain
Luxembourg
Legal structure
Open-end Investment Company
Base currency
USD
Classification
Product type
Benchmark
STOXX Global Breakthrough Healthcare Index
Asset class
Factors
N/A
Investment strategy
The Fund seeks to track the performance of an index composed of developed and emerging market companies which are generating significant revenues from specific sectors focused on pushing the boundaries in medical treatment and technology
Tax optimisation
PEA
France
UK Reporting Status
United Kingdom
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Built for professionals: access exclusive fund metrics and selection tools in Trackinsight Enterprise.
Enterprise Fund page features include:
Legal documents
Powerful buy-list integration
Fund data exports
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Advanced replication analysis
Advanced exposure look-through
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Enterprise
Trackinsight Enterprise helps professional and institutional ETF investors tackle operational, regulatory, and analytical challenges at every stage of the investment process.
Learn more about Trackinsight EnterpriseSimilar ETFs
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E/R
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E/R
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-7.52%
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Risk profile
Segment for quartile rank
Historical risk/return profile
| 3M | 1Y | 3Y | 5Y | |
|---|---|---|---|---|
| Returns | -4.98% | +14.22%  | +20.34% | -14.40% |
| Volatility | ||||
| Perf./Volatility | ||||
| Max drawdown |
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Synthetic Risk and Reward Indicator (SRRI)
UCITS
1
2
3
4
5
6
7
PRIIPS
1
2
3
4
5
6
7
Built for professionals: access exclusive risk metrics in Trackinsight Enterprise.
Enterprise
Trackinsight Enterprise helps professional and institutional ETF investors tackle operational, regulatory, and analytical challenges at every stage of the investment process.
Learn more about Trackinsight EnterpriseExposure
Countries
USA
65.47%
Switzerland
7.93%
Republic of Korea
4.86%
Japan
3.46%
Denmark
2.70%
United Kingdom
2.47%
Belgium
2.35%
Ireland
2.30%
Unavailable
0.22%
Other
8.23%
Sectors
Health Care
91.07%
Information Technology
1.61%
Unavailable
7.32%
Diversification
Total weight of top 15 holdings out of 173
Top 15 holdings
Data as of January 31, 2026
ILLUMINA
UCB
EXACT SCIENCES
IQVIA HOLDINGS INC
MODERNA INC
JOHNSON&JOHNSON
GENMAB
THERMO FISHER SCIENTIFIC
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NATERA
MERCK & CO INC
ROCHE
CH1391448177
BIOGEN INC
GILEAD SCIENCES
CELLTRION
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Built for professionals: access exclusive exposure metrics in Trackinsight Enterprise.
Enterprise
Trackinsight Enterprise helps professional and institutional ETF investors tackle operational, regulatory, and analytical challenges at every stage of the investment process.
Learn more about Trackinsight EnterpriseSustainability
Integrates ESG criteria
Yes
SDG
ESG Consensus® by Conser
Data as of December 31, 2025
MethodologyOur partner Conser gathers the industry's consensus on the business practices of the underlying holdings. We have computed the following metrics about 2B78 ETF's sustainability, based on their methodology.
ESG Consensus®
ESG Consensus® is based on the Final Sustainability Grade, which itself consists of 10 grades. Our partner Conser calculates the exact grade, based on market intelligence, using their proprietary ESG Consensus® methodology.
2B78’s has a Final Sustainability Grade of either A+, A, or A-.
A+
A
A-
B+
B
B-
C+
C
C-
D
This fund’s exact Final Sustainability Grade is available in Trackinsight Enterprise.
Learn more about Trackinsight EnterpriseHoldings review
91.87% of holdings have positive scoring
8.36% of holdings have negative scoring
13.35%
61.76%
16.77%
7.02%
Consensus levels
Strong
Medium
Weak
Built for professionals: access exclusive sustainability metrics in Trackinsight Enterprise.
Enterprise
Trackinsight Enterprise helps professional and institutional ETF investors tackle operational, regulatory, and analytical challenges at every stage of the investment process.
Learn more about Trackinsight EnterpriseReplication
Trackinsight replication rating:
Replication quality
Calculated over 12m, as of February 27, 2026
Tracking error
Tracking difference
Replication information
Index
STOXX Global Breakthrough Healthcare Index - USD
Index ticker
IXBRHLTU Index
Index dividend policy
NTR
Replication method
Replication model
Built for professionals: access exclusive replication metrics in Trackinsight Enterprise.
Enterprise
Trackinsight Enterprise helps professional and institutional ETF investors tackle operational, regulatory, and analytical challenges at every stage of the investment process.
Learn more about Trackinsight EnterpriseIssuer
iShares
iShares ID Card
Number of funds
1720
Total AuM
€4.9T
Expense ratio range
0.03% - 1.51%
Average expense ratio
0.285%
Top 5 funds by iShares
| AuM | ||
|---|---|---|
IVV | iShares Core S&P 500 ETF | €604.11B |
IEFA | iShares Core MSCI EAFE ETF | €145.9B |
AGG | iShares Core U.S. Aggregate Bond ETF | €120.51B |
IEMG | iShares Core MSCI Emerging Markets ETF | €118.19B |
CSSPX | iShares Core S&P 500 UCITS ETF | €112.42B |
Frequently asked questions about 2B78
What does iShares Healthcare Innovation UCITS ETF, 2B78, invest in?
2B78 is a Passive ETF. This ETF provides exposure to Other Equities.
Which benchmark or index does 2B78 replicate?
2B78 tracks the STOXX Global Breakthrough Healthcare Index - USD, through a optimized sampling replication method.
What is the Total Expense ratio (TER) of 2B78?
2B78 carries a total expense ratio (TER) of 0.4%, indicating the annual cost for holding the fund.
When was 2B78 launched?
2B78 was introduced to the market on September 8, 2016. It trades on Portugal, among other exchanges
Who is the ETF issuer of 2B78?
iShares Healthcare Innovation UCITS ETF, 2B78, is provided by iShares. Learn more about iShares here.
What is the current assets under management (AUM) of 2B78?
2B78 oversees €866M in assets as of March 13, 2026.
How has 2B78 performed lately?
Based on data from March 13, 2026, 2B78 returned -5.22% over the past month, -4.98% over the last three months and -4.90% year-to-date.
What are the latest inflows or outflows for 2B78?
As of March 13, 2026, 2B78 recorded net flows of -€7.7M over the last month and +€8.2M year-to-date.
Does 2B78 distribute dividends?
2B78 follows a capitalizing, meaning it reinvests income within the fund.
What are the main country or region exposures of 2B78?
As of January 31, 2026, 2B78 has significant geographic allocations in USA, Switzerland and Republic of Korea.
In which sector or theme does 2B78 invest in?
As of January 31, 2026, 2B78 focuses largely on Health Care and Information Technology.
How many securities does 2B78 hold and how diversified is it?
As of January 31, 2026, 2B78 holds 173 positions in its portfolio, with 29.40% of assets concentrated in its top 15 holdings.
What are the main positions in 2B78?
As of January 31, 2026, 2B78 top three holdings include ILLUMINA, UCB and EXACT SCIENCES.
What is the base currency of 2B78?
The base currency of 2B78 is USD.
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