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›ETF Providers›iShares›2B78
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2B78 ETF · iShares Healthcare Innovation UCITS ETF

The 2B78 Exchange Traded Fund (ETF) is provided by iShares. It is built to track an index: STOXX Global Breakthrough Healthcare Index. The 2B78 ETF provides physical exposure, so by buying it you actually own parts of all the 172 underlying holdings. The dividend policy is capitalization.
Last update 4/28/2026, 6:00 AM UTC
LIVE
CLOSED
This fund is part ofWorld Blended Cap1M perf.+11.01%
Last price
€7.26
-1.43%
1M perf.
-0.26%
1M flows
-€11M
AuM
€814M
E/R
0.4%
Rating
ESG Consensus®
esg grade icon
2B78
€7.26
-1.43%

Performance & flows

Segment for quartile rank
January 29, 2026 → April 29, 2026
0-12-10-8-6-4-2024%FEBMARAPRFEBMARAPR
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2B78
$8.41
-10.50%
World Blended Cap
+2.37%

Historic performance and flows

1M3M1Y3Y5YMTDQTDYTD
Perf.
-0.26%
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-10.50%
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+14.06%
icon
+13.09%
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-19.36%
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-2.46%
-2.46%
-6.59%
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Flows

Key fund info

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Main characteristics
Issuer
ISIN
IE00BYZK4776
AuM
€814M
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E/R
0.4%
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Replication rating
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ESG Consensus®
esg grade icon
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More details
NAV
4/29/2026
$8.41
1D NAV change
-1.52%
Dividend policy
Replication method
Direct (Physical)
Replication model
Optimized sampling
No. of holdings
172
Inception date
9/8/2016
Jurisdiction
Ireland
Distribution
Netherlands
Spain
Italy
Chile
Hungary
Legal structure
Open-end Investment Company
Base currency
USD
Classification
Product type
Benchmark
STOXX Global Breakthrough Healthcare Index
Asset class
Factors
N/A
Investment strategy
The Fund seeks to track the performance of an index composed of developed and emerging market companies which are generating significant revenues from specific sectors focused on pushing the boundaries in medical treatment and technology
Tax optimisation
PEA
France
UK Reporting Status
United Kingdom
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Risk profile

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Historical risk/return profile

3M1Y3Y5Y
Returns
-10.50%
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+14.06%
icon
+13.09%
icon
-19.36%
icon
Volatility
Perf./Volatility
Max drawdown
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Synthetic Risk and Reward Indicator (SRRI)
UCITS
1
2
3
4
5
6
7
PRIIPS
1
2
3
4
5
6
7
More exposure metrics are available, exclusively in Trackinsight Enterprise

Exposure

Countries
USA
65.46%
Switzerland
7.89%
Republic of Korea
4.26%
Japan
3.87%
United Kingdom
2.86%
Belgium
2.59%
Ireland
2.43%
Denmark
2.43%
Unavailable
0.17%
Other
8.05%
Sectors
Health Care
89.71%
Information Technology
1.44%
Unavailable
8.85%
Diversification
Total weight of top 15 holdings out of 172
Top 15 holdings
Data as of March 31, 2026
MODERNA INC
UCB
JOHNSON&JOHNSON
MERCK & CO INC
ILLUMINA
BIOGEN INC
GSK PLC
NOVARTIS
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GILEAD SCIENCES
BRISTOL-MYERS SQUIBB
NATERA
AMGEN-T
THERMO FISHER SCIENTIFIC
HOLOGIC
PFIZER
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More risk metrics are available, exclusively in Trackinsight Enterprise

Sustainability

Integrates ESG criteria
Yes
SDG

ESG Consensus® by Conser

Data as of February 27, 2026
Methodology

Our partner Conser gathers the industry's consensus on the business practices of the underlying holdings. We have computed the following metrics about 2B78 ETF's sustainability, based on their methodology.

Learn more about Conser

ESG Consensus®
esg grade icon

ESG Consensus® is based on the Final Sustainability Grade, which itself consists of 10 grades. Our partner Conser calculates the exact grade, based on market intelligence, using their proprietary ESG Consensus® methodology.


2B78’s has a Final Sustainability Grade of either A+, A, or A-.

This fund’s exact Final Sustainability Grade is available in Trackinsight Enterprise.
Learn more about Trackinsight Enterprise
Holdings review
90.44% of holdings have positive scoring
9.74% of holdings have negative scoring
12.54%
61.39%
16.51%
7.42%
Consensus levels
Strong
Medium
Weak
More sustainability metrics are available, exclusively in Trackinsight Enterprise

Replication

Trackinsight replication rating:
1-year trailing difference
As of March 31, 2026
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2B78
N/A
Replication quality
Calculated over 12m, as of March 31, 2026
Tracking error
Tracking difference
1-year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
Replication information
Index
Index ticker
Index dividend policy
Replication method
Replication model

Issuer

iShares
iShares ID Card
Number of funds
1740
Total AuM
€5.14T
Expense ratio range
0.03% - 1.51%
Average expense ratio
0.284%
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Frequently asked questions about 2B78

What does iShares Healthcare Innovation UCITS ETF, 2B78, invest in?

2B78 is a Passive ETF. This ETF provides exposure to Other Equities.

Which benchmark or index does 2B78 replicate?

2B78 tracks the STOXX Global Breakthrough Healthcare Index - USD, through a optimized sampling replication method.

What is the Total Expense ratio (TER) of 2B78?

2B78 carries a total expense ratio (TER) of 0.4%, indicating the annual cost for holding the fund.

When was 2B78 launched?

2B78 was introduced to the market on September 8, 2016. It trades on Netherlands, among other exchanges

Who is the ETF issuer of 2B78?

iShares Healthcare Innovation UCITS ETF, 2B78, is provided by iShares. Learn more about iShares here.

What is the current assets under management (AUM) of 2B78?

2B78 oversees €814M in assets as of April 29, 2026.

How has 2B78 performed lately?

Based on data from April 29, 2026, 2B78 returned -0.26% over the past month, -10.50% over the last three months and -6.59% year-to-date.

What are the latest inflows or outflows for 2B78?

As of April 29, 2026, 2B78 recorded net flows of -€11M over the last month and -€18M year-to-date.

Does 2B78 distribute dividends?

2B78 follows a capitalizing, meaning it reinvests income within the fund.

What are the main country or region exposures of 2B78?

As of March 31, 2026, 2B78 has significant geographic allocations in USA, Switzerland and Republic of Korea.

In which sector or theme does 2B78 invest in?

As of March 31, 2026, 2B78 focuses largely on Health Care and Information Technology.

How many securities does 2B78 hold and how diversified is it?

As of March 31, 2026, 2B78 holds 172 positions in its portfolio, with 30.82% of assets concentrated in its top 15 holdings.

What are the main positions in 2B78?

As of March 31, 2026, 2B78 top three holdings include MODERNA INC, UCB and JOHNSON&JOHNSON.

What is the base currency of 2B78?

The base currency of 2B78 is USD.

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